The Feulgen reaction is pivotal in histology for several reasons:
- Specificity: It is one of the few staining techniques that specifically target DNA, allowing for precise identification of nuclear material. - Quantification: The intensity of the magenta color correlates with the amount of DNA present, enabling quantitative studies. - Research and Diagnostics: It is used extensively in cytogenetics, cancer research, and diagnostics to study cellular proliferation, ploidy, and other nuclear characteristics.