The heterogeneity of stem cell populations is critical for several reasons:
Tissue Homeostasis: Different subpopulations contribute to the balanced renewal of tissues, ensuring that specialized cells are replenished as needed. Regenerative Capacity: A diverse stem cell pool enhances the ability of tissues to repair and regenerate following damage. Disease Progression: Understanding heterogeneity can shed light on how certain subpopulations might contribute to disease states, such as cancer.