What Factors Contribute to Stem Cell Heterogeneity?
Several factors contribute to the heterogeneity within stem cell populations:
Intrinsic Factors: Genetic and epigenetic variations among stem cells can lead to differences in their properties and behavior. Extrinsic Factors: The microenvironment, including signals from surrounding cells and the extracellular matrix, influences stem cell behavior and heterogeneity. Developmental Stage: Stem cells at different stages of development can exhibit varying levels of potency and differentiation potential.
