Resistance to apoptosis is significant because it can lead to uncontrolled cell proliferation and the development of diseases such as cancer. Normally, cells that are damaged or no longer needed are eliminated through apoptosis. However, when cells become resistant to apoptosis, they can survive and proliferate even when they should not. This resistance is a hallmark of many cancers, allowing malignant cells to evade cell death and continue growing unchecked.
