Misfolded proteins can lead to a variety of diseases, collectively termed as protein misfolding diseases or conformational diseases. Examples include:
Alzheimer's Disease: Characterized by the accumulation of misfolded amyloid-beta proteins. Parkinson's Disease: Associated with the aggregation of misfolded alpha-synuclein proteins. Cystic Fibrosis: Caused by mutations leading to misfolding of the CFTR protein.