Understanding the 3D architecture of tissues is crucial for several reasons:
Spatial Relationships: Cells, extracellular matrix, and other components interact in complex ways that are best understood in three dimensions. Functional Insights: The function of many tissues and organs is inherently linked to their 3D structure. For instance, the intricate network of blood vessels in the liver or the branching patterns of neurons in the brain. Pathology: Many diseases, including cancer, involve changes in tissue architecture that can be better understood and diagnosed through 3D imaging.
