DAT plays a critical role in regulating dopamine levels, which are essential for various physiological processes, including motor control, reward, and cognition. Abnormal DAT function is implicated in several neurological and psychiatric disorders. For instance, reduced DAT activity is associated with Parkinson's disease, while altered DAT function is linked to conditions like ADHD and substance abuse disorders. Understanding the histological distribution and function of DAT is crucial for developing targeted therapies for these conditions.
