Where is the GAP Domain Found in Histological Samples?

In histological samples, GAP domains can be found in various tissues depending on the specific GTPase they interact with. For instance, RasGAPs are often found in tissues with high rates of cell division such as epithelial tissues. RhoGAPs, on the other hand, are more prevalent in tissues that require dynamic cytoskeletal arrangements, such as muscle and neural tissues. Immunohistochemistry techniques can be used to visualize the presence and localization of GAP domains in these tissues.