How Does the GAP Domain Influence Cellular Processes?
The GAP domain influences various cellular processes by regulating the activity of different GTPases. For example, the RasGAP domain interacts with the Ras protein, which is involved in cell proliferation and differentiation. By inactivating Ras, RasGAP prevents uncontrolled cell division, thereby acting as a tumor suppressor. Similarly, RhoGAP domains regulate Rho GTPases, which are key players in cytoskeletal dynamics and cell mobility.
