Where is Methylpurine DNA Glycosylase Found in Tissues?
MPG is ubiquitously expressed in various tissues, reflecting its fundamental role in cellular homeostasis. However, the expression levels can vary depending on the tissue type and the cell's proliferative state. High levels of MPG are often observed in tissues with high rates of cell division, such as the bone marrow, intestinal epithelium, and embryonic tissues. Its presence is crucial in these rapidly dividing cells to counteract the increased risk of DNA damage.
