What Therapeutic Implications do Lipid Mediators Have?
Understanding the role of lipid mediators in various diseases has led to the development of therapeutic interventions targeting these molecules. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzymes to reduce the production of pro-inflammatory prostaglandins, providing relief from pain and inflammation. Additionally, leukotriene receptor antagonists are used in the treatment of asthma and allergic rhinitis. The discovery of SPMs has also opened new avenues for developing therapies that promote the resolution of inflammation without immunosuppression.
