What Techniques are Used to Study MMPs in Histology?
Several techniques are employed to study MMPs in histological samples:
- Immunohistochemistry (IHC): Used to localize MMP expression in tissue sections. - In Situ Hybridization (ISH): Detects MMP mRNA within tissue samples. - Zymography: A gel electrophoresis technique to analyze MMP activity based on their ability to degrade gelatin or casein embedded in the gel.