What Challenges Exist in Identifying Microorganisms in Histology?
Several challenges can complicate the identification of microorganisms:
- Artifact Introduction: Contamination during sample preparation can lead to false positives. - Morphological Similarity: Some microorganisms have similar appearances under the microscope, making differentiation difficult. - Tissue Processing: The process of fixing and embedding tissues can sometimes obscure or damage microorganisms. - Sensitivity of Staining Techniques: Not all stains will work equally well for all microorganisms, potentially leading to missed diagnoses.
