What Techniques Are Used to Study Genetic Interactions in Histology?
Several advanced techniques are employed to study genetic interactions within tissues:
- Immunohistochemistry: This technique uses antibodies to detect specific proteins within tissue sections, providing insights into gene expression and protein localization. - In situ hybridization: This method allows for the visualization of specific RNA molecules within tissue samples, offering a view of gene expression patterns. - CRISPR/Cas9: This genome-editing tool can be used to create targeted mutations, enabling the study of gene function and interactions. - Single-cell RNA sequencing: This technique provides a detailed view of gene expression at the single-cell level, revealing the complexity of genetic interactions within heterogeneous tissues.
