What Techniques are Used in Histological Analysis of CAR T Cell Therapy?
Various histological techniques are utilized to study the effects of CAR T cell therapy:
- Hematoxylin and Eosin (H&E) Staining: Basic staining to view the general architecture and cellular details. - Immunohistochemistry (IHC): Used to detect specific proteins and markers on the cells. - Flow Cytometry: Although not strictly histological, it's often used in conjunction to analyze cell populations. - Tissue Imaging: Advanced imaging techniques like confocal microscopy can provide detailed views of tissue architecture and cell interactions.
