PDK1 is a key regulator of the PI3K/Akt signaling pathway, which is vital for controlling cell growth and survival. It phosphorylates and activates Akt, a kinase that promotes cell survival and growth. Through this pathway, PDK1 influences numerous cellular processes including metabolism, protein synthesis, and apoptosis. Disruptions in PDK1 activity can lead to various diseases, such as cancer and metabolic disorders.
