Phagocytosis: They ingest and destroy pathogens, dead cells, and other debris. Antigen Presentation: Macrophages process and present antigens to T cells, initiating and shaping the adaptive immune response. Cytokine Production: They produce a range of cytokines that modulate the immune response, including interleukins and Tumor Necrosis Factor (TNF). Tissue Repair: Macrophages contribute to wound healing and tissue repair by clearing dead cells and promoting tissue remodeling.