What role does in situ hybridization (ISH) play in histological analysis?
In situ hybridization (ISH) is a technique that allows for the localization of specific nucleic acid sequences within tissue sections. By using labeled complementary RNA or DNA probes, ISH can detect the presence and distribution of mRNA or DNA sequences. This method is particularly useful for studying gene expression patterns and chromosomal abnormalities within the histological context.
