How does histological examination support the diagnosis?
Histological examination involves staining the tumor tissue with various dyes and examining the cells under a microscope. Common staining techniques include Hematoxylin and Eosin (H&E) staining, which highlights the general structure of the tissue. Immunohistochemistry is also used to detect specific proteins within the cells, providing additional diagnostic and prognostic information. For instance, the expression of GFAP (glial fibrillary acidic protein) can identify astrocytic tumors, while synaptophysin staining can help identify neuronal tumors.
