What role does GABA play in neurological disorders?
GABAergic dysfunction has been implicated in various neurological and psychiatric disorders such as epilepsy, anxiety disorders, depression, and schizophrenia. For example, a deficiency in GABA levels or GABA receptor function can lead to increased neuronal excitability, contributing to the development of seizures in epilepsy. On the other hand, drugs that enhance GABAergic activity, such as benzodiazepines, are commonly used to treat anxiety and insomnia by promoting relaxation and sedation.
