In histological studies, GABA can be visualized using immunohistochemistry techniques that involve the use of antibodies specific to GABA or GABAergic enzymes like GAD. These antibodies can be tagged with fluorescent markers or enzymes that produce a colorimetric reaction, allowing researchers to identify and quantify GABAergic neurons and their distribution in tissue sections. Additionally, techniques such as in situ hybridization can be used to detect mRNA expression of GABA-related genes.
