What Role Do Transcription Factors Play in Histology?
Transcription factors are pivotal in guiding the differentiation and function of cells within tissues. For instance, the transcription factor Myogenin is essential for muscle differentiation, while GATA3 is crucial for the development of various tissues, including the mammary gland and immune cells. These factors bind to specific DNA sequences, recruiting or blocking the transcriptional machinery and thereby regulating gene expression.