What Are the Implications of Transcriptional Dysregulation?
Transcriptional dysregulation can lead to a variety of diseases and disorders. For example, mutations in transcription factors or epigenetic regulators can result in abnormal gene expression, contributing to conditions such as cancer, autoimmune diseases, and developmental disorders. In cancer, for instance, the overexpression of oncogenes or the silencing of tumor suppressor genes due to transcriptional dysregulation can promote uncontrolled cell proliferation and tumor growth.
