kidney pathology

What Role Do Special Stains and Immunofluorescence Play in Kidney Pathology?

Special stains and immunofluorescence are invaluable in kidney pathology. Special stains, like Periodic Acid-Schiff (PAS) and Silver stain, highlight specific tissue components, aiding in identifying changes like basement membrane thickening. Immunofluorescence detects immune deposits in glomeruli by using antibodies tagged with fluorescent dyes, which is crucial for diagnosing immune-mediated glomerular diseases.

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