What Changes Occur in the Stratum Spinosum During Skin Disorders?
In various skin disorders such as psoriasis and eczema, the stratum spinosum can show significant changes. For example, in psoriasis, there is an increased rate of keratinocyte proliferation, leading to a thickened stratum spinosum. In eczema, inflammation can cause the breakdown of desmosomes, weakening the structural integrity of this layer.
