What are the Common Histological Techniques Used in Pharmaceutical Development?
Several histological techniques are commonly employed in pharmaceutical research. These include:
Hematoxylin and Eosin (H&E) Staining: A fundamental technique for general tissue visualization. Immunohistochemistry (IHC): Used to detect specific proteins within tissues, helping to identify cellular responses to drugs. In Situ Hybridization (ISH): Allows for the detection of specific nucleic acid sequences within tissue samples. Electron Microscopy: Provides ultra-structural details of cells and tissues, revealing drug effects at the subcellular level.
These techniques collectively enable a comprehensive analysis of how drugs interact with tissues at multiple levels of resolution.
