What is the Significance of Polymorphisms in Cancer Histology?
In cancer histology, genetic polymorphisms can play a crucial role in tumor development, progression, and response to treatment. Polymorphisms in oncogenes and tumor suppressor genes such as TP53 and KRAS can lead to abnormal cell growth and malignancy. Histological studies often reveal the impact of these polymorphisms on tissue architecture, aiding in diagnosis and prognostication.