What is the Significance of MART-1 in Melanoma Diagnosis?
MART-1 is significant in the diagnosis of melanoma because it is highly specific to melanocytes, the cells that give rise to melanoma. Its presence can help distinguish melanoma from other types of skin lesions or tumors. The use of MART-1 as a marker in pathology helps in confirming the diagnosis, especially in cases where the morphological features alone are not definitive.
