melanoma antigen recognized by t cells

How is MART-1 Detected in Histological Studies?

In histological studies, MART-1 can be detected using various techniques such as immunohistochemistry (IHC). IHC involves the use of antibodies that specifically bind to MART-1. These antibodies are often labeled with a colorimetric enzyme or a fluorescent dye, which makes the antigen-antibody complexes visible under a microscope. This allows researchers and clinicians to identify the presence and distribution of melanoma cells in tissue samples.

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