What is the Role of Myogenin in Muscle Differentiation?
Myogenin plays a crucial role in the terminal differentiation of muscle cells. It acts by binding to E-box sequences in the promoters of muscle-specific genes, thereby activating their transcription. This leads to the expression of structural proteins such as myosin and actin, which are essential for muscle fiber formation. Myogenin also interacts with other transcription factors and co-factors to coordinate the complex process of muscle differentiation and maturation.
