Histological examination of lymphomas involves assessing lymph node biopsies. Key features include:
Reed-Sternberg Cells: These large, binucleate cells with prominent nucleoli are indicative of Hodgkin lymphoma. Follicular Pattern: Seen in follicular lymphoma, where malignant cells form nodular aggregates. Diffuse Pattern: In DLBCL, the lymph node architecture is effaced by a diffuse proliferation of large lymphoid cells.
