stratum granulosum

What is the Role of Keratohyalin Granules?

Keratohyalin granules are essential for the process of keratinization. They contain large amounts of profilaggrin, which is cleaved into filaggrin in the stratum corneum. Filaggrin plays a vital role in binding keratin fibers together, leading to the formation of a strong, protective layer. These granules also contain other proteins and enzymes that contribute to the cross-linking of keratin fibers and the formation of a hydrophobic barrier.

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