muscle degeneration

What are the Histological Features of Muscle Degeneration?

In muscle degeneration, several histological changes can be observed:
1. Atrophy: This is the reduction in muscle fiber size. It is often accompanied by a decrease in the number of muscle fibers.
2. Fibrosis: The replacement of muscle tissue with fibrous connective tissue. This is often a response to chronic damage.
3. Necrosis: The death of muscle cells, which can lead to the formation of fibrotic scar tissue.
4. Inflammation: Presence of inflammatory cells such as macrophages and lymphocytes around the damaged muscle fibers.

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