What is the role of cellular injury in disease mechanisms?
Cellular injury is a fundamental concept in the mechanisms of disease. When cells are exposed to harmful stimuli, they can undergo reversible or irreversible injury. Reversible injury allows cells to recover if the stimulus is removed. However, irreversible injury leads to cell death, which can manifest as either necrosis or apoptosis. Necrosis is characterized by uncontrolled cell death resulting in inflammation, while apoptosis is a programmed cell death that occurs without inflammation.
