mechanisms of disease

How do genetic mutations impact tissue pathology?

Genetic mutations can lead to a variety of diseases by altering normal cellular functions. These mutations can either be inherited or acquired. Inherited mutations are present in every cell of the body and can lead to diseases such as cystic fibrosis, sickle cell anemia, and muscular dystrophy. Acquired mutations, such as those caused by environmental factors, can result in cancer. Histological analysis of tissues affected by genetic mutations often reveals abnormal cell morphology, disrupted tissue architecture, and the presence of abnormal proteins.

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