How do supplementary tests enhance diagnostic accuracy?
Supplementary tests enhance diagnostic accuracy by providing additional layers of information:
Immunohistochemistry can confirm the presence of specific proteins that are characteristic of certain cell types or disease states. Special stains can reveal structural details not visible with standard H&E staining, such as fungal organisms or amyloid deposits. In Situ Hybridization can pinpoint the exact location of genetic abnormalities within the tissue context. Molecular pathology techniques can identify genetic mutations that may be driving a disease and suggest potential therapeutic targets.