The FUS-DDIT3 fusion gene is a genetic abnormality often associated with certain types of cancers, most notably myxoid liposarcoma. This fusion gene results from a translocation between chromosomes 12 and 16, specifically t(12;16)(q13;p11). The FUS gene on chromosome 16 fuses with the DDIT3 gene on chromosome 12, leading to the production of a hybrid protein that disrupts normal cellular functions.
