What is the Functional Significance of Cytochrome P450 in Histology?
CYP450 enzymes are essential for the metabolic processing of drugs and toxins, which has significant implications for pharmacology and toxicology. In histological studies, the distribution and expression levels of CYP450 can help predict how different tissues handle various substances. For instance, high expression of CYP3A4 in the liver is crucial for the metabolism of many drugs, thus affecting their efficacy and toxicity.
