Cytochrome P450 (CYP450) is a superfamily of enzymes that play a crucial role in the metabolism of various substances within the body. These enzymes are found primarily in the liver, but they are also present in other tissues such as the intestines, lungs, and kidneys. CYP450 enzymes are involved in the oxidation of organic substances and are essential for the detoxification of xenobiotics, as well as the metabolism of endogenous compounds like steroids and fatty acids.