What Cells are Found in the Intestinal Crypt Niche?
The intestinal crypt niche contains several types of cells, including:
1. Stem cells: These are located at the base of the crypt and are responsible for generating all the different cell types in the intestinal epithelium. 2. Paneth cells: Located next to the stem cells, they secrete antimicrobial peptides and support stem cell function. 3. Transit amplifying cells: These are rapidly dividing cells that arise from stem cells and differentiate as they move up the crypt. 4. Goblet cells: These cells produce mucus to protect the epithelium and are found along the sides of the crypt and on the villi. 5. Enteroendocrine cells: These cells release hormones that regulate various functions of the gastrointestinal tract.
