What is the Functional Importance of Histone Acetylation?
Histone acetylation is essential for various cellular processes, including:
- Gene Regulation: By modulating accessibility to DNA, histone acetylation plays a pivotal role in the regulation of gene expression. - DNA Repair: Acetylation of histones is involved in the recruitment of DNA repair proteins to sites of damage. - Cell Cycle Progression: Proper acetylation patterns are necessary for the correct progression through the cell cycle. - Differentiation and Development: Histone acetylation patterns are dynamic and change as cells differentiate and develop.
