The primary function of the PSD protein complex is to ensure efficient signal transduction at the synapse by clustering neurotransmitter receptors and linking them to intracellular signaling pathways. This clustering enhances the responsiveness of the postsynaptic neuron to neurotransmitters and contributes to synaptic plasticity, which is essential for learning and memory. Additionally, the PSD complex provides structural support and regulates synaptic strength and stability.
