What is the Difference Between Apoptosis and Necrosis in Nuclear Condensation?
While nuclear condensation occurs in both apoptosis and necrosis, the context and characteristics differ:
1. Apoptosis: - Controlled Process: Apoptosis is a regulated, orderly process leading to cell death without causing inflammation. - Chromatin Condensation: Chromatin aggregates into well-defined, dense masses. - Cell Fragmentation: The cell breaks into apoptotic bodies, which are phagocytosed by neighboring cells.
2. Necrosis: - Uncontrolled Process: Necrosis is a result of acute cellular injury, leading to uncontrolled cell death and inflammation. - Chromatin Clumping: Chromatin may clump but lacks the orderly condensation seen in apoptosis. - Cell Swelling: Necrotic cells often swell and burst, releasing their contents into the surrounding tissue.
