Given its role in regulating cell motility, adhesion, and signaling, VASP has significant clinical implications. Dysregulation of VASP activity is associated with various pathological conditions, including cardiovascular diseases, atherosclerosis, and cancer. For instance, altered VASP phosphorylation states can contribute to abnormal platelet function, leading to thrombotic disorders. Understanding VASP's functions and regulatory mechanisms can aid in developing therapeutic strategies targeting these diseases.
