Cryogenic Scanning Electron Microscopy (Cryo-SEM) is a specialized technique used to observe the ultrastructure of biological and non-biological specimens at cryogenic temperatures. This method involves rapidly freezing samples to preserve their native state and then examining them under a scanning electron microscope. The primary advantage of Cryo-SEM is its ability to maintain the water content and structural integrity of samples, which is crucial for accurate histological analysis.
