Creatine kinase (CK), also known as creatine phosphokinase (CPK), is an enzyme primarily found in the heart, brain, and skeletal muscles. It plays a crucial role in cellular energy homeostasis by catalyzing the conversion of creatine and adenosine triphosphate (ATP) to phosphocreatine and adenosine diphosphate (ADP). This reaction is vital for the storage and release of energy in muscle tissues.