Class switch recombination (CSR) is a biological process that occurs in B cells within the germinal centers of lymphoid tissues. During CSR, the constant region of the immunoglobulin heavy chain is changed, enabling a B cell to produce a different class of antibody (IgA, IgE, or IgG) while retaining the same antigen specificity. This process is crucial for the adaptive immune response as it allows for a more versatile and effective response to pathogens.
