What is the Function of von Willebrand Factor in Hemostasis?
In hemostasis, vWF has two main functions. First, it binds to and stabilizes Factor VIII, protecting it from rapid degradation. Second, it acts as a bridge between platelets and the subendothelial matrix, particularly collagen, at injury sites. This allows platelets to adhere to the damaged vessel wall and form a platelet plug, which is essential for stopping bleeding.
