CD25, also known as the Interleukin-2 receptor alpha chain (IL-2Rα), is a protein that plays a crucial role in the immune system. It is primarily expressed on the surface of activated T cells, regulatory T cells (Tregs), and some B cells. CD25 is part of the high-affinity IL-2 receptor complex, which is essential for the growth, proliferation, and differentiation of T cells.