NIAID employs a variety of histological techniques, including:
Light microscopy: Used for examining stained tissue sections to identify cellular and structural abnormalities. Immunohistochemistry (IHC): Utilizes antibodies to detect specific proteins within tissues, helping to identify cellular markers and pathogen presence. Electron microscopy: Provides high-resolution images of tissue ultrastructure, aiding in the study of cellular organelles and microbial interactions. In situ hybridization (ISH): Detects specific nucleic acid sequences within tissues, useful for identifying pathogens and gene expression patterns.
